| Date | Teams | Spread | Money | Total |
|---|---|---|---|---|
| Saturday, Apr. 20, 02:20 pm |
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| Milwaukee Brewers at | (+1.5) -178 | +110 | (O: 8.5) -105 | |
| St. Louis Cardinals | (-1.5) +158 | -120 | (U: 8.5) -115 | |
| Saturday, Apr. 20, 02:20 pm |
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| Miami Marlins - Game #1 at | +140 | |||
| Chicago Cubs - Game #1 | -153 | |||
| Saturday, Apr. 20, 04:10 pm |
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| Arizona Diamondbacks at | (-1.5) 138 | -118 | (O: 8) -110 | |
| San Francisco Giants | (+1.5) -158 | +108 | (U: 8) -110 | |
| Saturday, Apr. 20, 01:10 pm |
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| Tampa Bay Rays at | (+1.5) -176 | +116 | (O: 8) -115 | |
| New York Yankees | (-1.5) +156 | -126 | (U: 8) -105 | |
| Saturday, Apr. 20, 02:15 pm |
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| Detroit Tigers at | (+1.5) -185 | +123 | (O: 7.5) -112 | |
| Minnesota Twins | (-1.5) +165 | -134 | (U: 7.5) -108 | |
| Saturday, Apr. 20, 06:15 pm |
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| Oakland Athletics at | (+1.5) -150 | +149 | (O: 8) -112 | |
| Cleveland Guardians | (-1.5) +130 | -163 | (U: 8) -108 | |
| Saturday, Apr. 20, 07:15 pm |
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| Baltimore Orioles at | (-1.5) 132 | -131 | (O: 7.5) -115 | |
| Kansas City Royals | (+1.5) -152 | +121 | (U: 7.5) -105 | |
| Saturday, Apr. 20, 04:10 pm |
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| Boston Red Sox at | (+1.5) -198 | +104 | (O: 8) +105 | |
| Pittsburgh Pirates | (-1.5) +173 | -114 | (U: 8) -125 | |
| Saturday, Apr. 20, 04:10 pm |
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| Houston Astros at | (-1.5) -115 | -168 | (O: 8.5) -117 | |
| Washington Nationals | (+1.5) -105 | +154 | (U: 8.5) -103 | |
| Saturday, Apr. 20, 06:10 pm |
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| Chicago White Sox at | (+1.5) 110 | +246 | (O: 7.5) -125 | |
| Philadelphia Phillies | (-1.5) -130 | -280 | (U: 7.5) +105 | |
| Saturday, Apr. 20, 06:45 pm |
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| Los Angeles Angels at | (+1.5) -175 | +112 | (O: 9.5) -109 | |
| Cincinnati Reds | (-1.5) +155 | -122 | (U: 9.5) -111 | |
| Saturday, Apr. 20, 07:25 pm |
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| Texas Rangers at | (+1.5) -145 | +138 | (O: 9.5) -105 | |
| Atlanta Braves | (-1.5) +125 | -150 | (U: 9.5) -115 | |
| Saturday, Apr. 20, 07:40 pm |
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| Miami Marlins - Game #2 at | +179 | |||
| Chicago Cubs - Game #2 | -196 |