| Date | Teams | Spread | Money | Total |
|---|---|---|---|---|
| Friday, May. 03, 06:45 pm |
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| Colorado Rockies at | (+1.5) -136 | +157 | (O: 8) -110 | |
| Pittsburgh Pirates | (-1.5) +116 | -172 | (U: 8) -110 | |
| Friday, May. 03, 06:45 pm |
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| San Francisco Giants at | (+1.5) -153 | +148 | (O: 7) -117 | |
| Philadelphia Phillies | (-1.5) +133 | -162 | (U: 7) -103 | |
| Friday, May. 03, 09:40 pm |
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| San Diego Padres at | (+1.5) -217 | -111 | (O: 9) -120 | |
| Arizona Diamondbacks | (-1.5) +187 | +101 | (U: 9) +100 | |
| Friday, May. 03, 10:10 pm |
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| Atlanta Braves at | (+1.5) -205 | -105 | (O: 9.5) +105 | |
| Los Angeles Dodgers | (-1.5) +175 | -105 | (U: 9.5) -125 | |
| Friday, May. 03, 07:05 pm |
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| Detroit Tigers at | (+1.5) -142 | +148 | (O: 7.5) -115 | |
| New York Yankees | (-1.5) +122 | -162 | (U: 7.5) -105 | |
| Friday, May. 03, 07:15 pm |
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| Los Angeles Angels at | (+1.5) -126 | +176 | (O: 7.5) -102 | |
| Cleveland Guardians | (-1.5) +106 | -193 | (U: 7.5) -118 | |
| Friday, May. 03, 07:45 pm |
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| Texas Rangers at | (+1.5) -197 | +102 | (O: 8.5) -113 | |
| Kansas City Royals | (-1.5) +172 | -112 | (U: 8.5) -107 | |
| Friday, May. 03, 08:15 pm |
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| Seattle Mariners at | (+1.5) -205 | +102 | (O: 8) -118 | |
| Houston Astros | (-1.5) +175 | -112 | (U: 8) -102 | |
| Friday, May. 03, 08:15 pm |
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| Boston Red Sox at | (+1.5) -195 | +107 | (O: 7.5) -117 | |
| Minnesota Twins | (-1.5) +170 | -117 | (U: 7.5) -103 | |
| Friday, May. 03, 06:40 pm |
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| Baltimore Orioles at | (+1.5) -190 | +103 | (O: 9) -115 | |
| Cincinnati Reds | (-1.5) +165 | -113 | (U: 9) -105 | |
| Friday, May. 03, 06:50 pm |
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| Toronto Blue Jays at | (-1.5) -131 | -198 | (O: 8.5) -107 | |
| Washington Nationals | (+1.5) +111 | +180 | (U: 8.5) -113 | |
| Friday, May. 03, 06:55 pm |
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| New York Mets at | (+1.5) -168 | +126 | (O: 8) -114 | |
| Tampa Bay Rays | (-1.5) +148 | -137 | (U: 8) -106 | |
| Friday, May. 03, 08:20 pm |
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| Chicago White Sox at | (+1.5) 113 | +246 | (O: 7.5) -112 | |
| St. Louis Cardinals | (-1.5) -133 | -280 | (U: 7.5) -108 | |
| Friday, May. 03, 09:45 pm |
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| Miami Marlins at | (+1.5) -169 | +134 | (O: 7.5) -119 | |
| Oakland Athletics | (-1.5) +149 | -146 | (U: 7.5) -101 | |
| Saturday, May. 04, 02:25 pm |
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| Milwaukee Brewers at | +110 | |||
| Chicago Cubs | -120 | |||
| Saturday, May. 04, 04:10 pm |
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| Colorado Rockies at | +178 | (O: 8) +103 | ||
| Pittsburgh Pirates | -195 | (U: 8) -123 | ||
| Saturday, May. 04, 06:10 pm |
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| San Francisco Giants at | +151 | (O: 7.5) -115 | ||
| Philadelphia Phillies | -165 | (U: 7.5) -105 | ||
| Saturday, May. 04, 08:15 pm |
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| San Diego Padres at | +106 | (O: 9) -110 | ||
| Arizona Diamondbacks | -116 | (U: 9) -110 | ||
| Saturday, May. 04, 09:15 pm |
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| Atlanta Braves at | +148 | (O: 9) -105 | ||
| Los Angeles Dodgers | -162 | (U: 9) -115 | ||
| Saturday, May. 04, 01:10 pm |
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| Detroit Tigers at | +138 | (O: 8) -115 | ||
| New York Yankees | -150 | (U: 8) -105 | ||
| Saturday, May. 04, 06:15 pm |
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| Los Angeles Angels at | +125 | (O: 7.5) -125 | ||
| Cleveland Guardians | -136 | (U: 7.5) +105 | ||
| Saturday, May. 04, 07:15 pm |
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| Texas Rangers at | -109 | (O: 9) -115 | ||
| Kansas City Royals | -101 | (U: 9) -105 | ||
| Saturday, May. 04, 07:20 pm |
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| Seattle Mariners at | +122 | (O: 8) -105 | ||
| Houston Astros | -133 | (U: 8) -115 | ||
| Saturday, May. 04, 02:20 pm |
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| Chicago White Sox at | +158 | (O: 8) -110 | ||
| St. Louis Cardinals | -173 | (U: 8) -110 | ||
| Saturday, May. 04, 04:10 pm |
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| Toronto Blue Jays at | -163 | (O: 8.5) +100 | ||
| Washington Nationals | +149 | (U: 8.5) -120 | ||
| Saturday, May. 04, 04:12 pm |
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| Miami Marlins at | +105 | (O: 8) -104 | ||
| Oakland Athletics | -115 | (U: 8) -116 | ||
| Saturday, May. 04, 06:45 pm |
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| Baltimore Orioles at | -112 | (O: 9) -125 | ||
| Cincinnati Reds | +102 | (U: 9) +105 | ||
| Saturday, May. 04, 07:20 pm |
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| New York Mets at | +102 | (O: 8) -115 | ||
| Tampa Bay Rays | -112 | (U: 8) -105 |